Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protective Low-Frequency Variants for Preeclampsia in the Fms Related Tyrosine Kinase 1 Gene in the Finnish Population.

Hypertension (Dallas, Tex. : 1979) - 1 Aug 2017

Lokki A Inkeri, Daly Emma, Triebwasser Michael, Kurki Mitja I, Roberson Elisha D O, Häppölä Paavo, Auro Kirsi, Perola Markus, Heinonen Seppo, Kajantie Eero, Kere Juha, Kivinen Katja, Pouta Anneli, Salmon Jane E, Meri Seppo, Daly Mark, Atkinson John P, Laivuori Hannele

Abstract excerpt

Preeclampsia is a common pregnancy-specific vascular disorder characterized by new-onset hypertension and proteinuria during the second half of pregnancy. Predisposition to preeclampsia is in part heritable. It is associated with an increased risk of cardiovascular disease later in life. We have sequenced 124 candidate genes implicated in preeclampsia to pinpoint genetic variants contributing to predisposition to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Finland
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension

Share to Pre-Eclampsia

Share to Pregnancy

Share to Protective Factors

Share to Vascular Endothelial Growth Factor Receptor-1

Source

Open in PubMed Open full text

Identifiers

PMID: 28652462
DOI: 10.1161/HYPERTENSIONAHA.117.09406
PMCID: PMC5535812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protective Low-Frequency Variants for Preeclampsia in the Fms Related Tyrosine Kinase 1 Gene in the Finnish Population.PMID 28652462Read ↗

Genetic predisposition to preeclampsia is conferred by fetal DNA variants near FLT1, a gene involved in the regulation of angiogenesis.Semantic proximity Read ↗

Exome sequencing in pooled DNA samples to identify maternal pre-eclampsia risk variants.Semantic proximity Read ↗

GWAS of preeclampsia and hypertensive disorders of pregnancy uncovers genes related to cardiometabolic, endothelial and placental functionSemantic proximity Read ↗

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia.Semantic proximity Read ↗

Risk of preeclampsia in patients with genetic predisposition to common medical conditions: a case-control studySemantic proximity Read ↗

Cohort profile: the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC)Semantic proximity Read ↗

Genetic Risk Factors Associated With Preeclampsia and Hypertensive Disorders of PregnancySemantic proximity Read ↗

Whole-exome sequencing in multiplex preeclampsia families identifies novel candidate susceptibility genesSemantic proximity Read ↗

Preeclampsia Genomic Susceptibility Factors in Populations of African Ancestry: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

The non-traditional and familial risk factors for preeclampsia in the FINNPEC cohortSemantic proximity Read ↗

The role of genetics in maternal susceptibility to preeclampsia in women of African ancestry.Semantic proximity Read ↗

Susceptibility loci for preeclampsia on chromosomes 2p25 and 9p13 in Finnish families.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.