Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism and risk of preeclampsia: an updated meta-analysis based on 51 studies.

Archives of medical research - 1 Apr 2013

Wang Xi-mei, Wu Hai-yan, Qiu Xu-jun

Abstract excerpt

BACKGROUND AND AIMS: The methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism has been considered to be associated with preeclampsia (PE), but the results from previous studies were conflicting. The present study aimed at investigating the frequency of preeclampsia according to the distribution polymorphism using a meta-analysis on the published studies. METHODS: The English and Chinese databases...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asia, Eastern
Share to Confidence Intervals

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Odds Ratio

Share to Pre-Eclampsia

Share to Pregnancy

Share to Sample Size

Share to White People

Source

Identifiers

PMID: 23395424
DOI: 10.1016/j.arcmed.2013.01.011

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism and risk of preeclampsia: an updated meta-analysis based on 51 studies.PMID 23395424Read ↗

Folate metabolism gene polymorphisms MTHFR C677T and A1298C and risk for preeclampsia: a meta-analysis.Semantic proximity Read ↗

Meta-analysis of the methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to pre-eclampsia.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene C677T, A1298C polymorphisms and pre-eclampsia risk: a meta-analysis.Semantic proximity Read ↗

Genetic variants in 3'-UTRs of MTHFR in the pregnancies complicated with preeclampsia and bioinformatics analysis.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene (C677T) mutation as a genetic risk factor for preeclampsia in Ethiopian pregnant women.Semantic proximity Read ↗

Association Between MTHFR Polymorphisms and the Risk of Essential Hypertension: An Updated Meta-analysisSemantic proximity Read ↗

Associations between AGT, MTHFR, and VEGF gene polymorphisms and preeclampsia in the Chinese population.Semantic proximity Read ↗

Association of methylenetetrahydrofolate reductase gene C677T polymorphism with polycystic ovary syndrome risk: a systematic review and meta-analysis update.Semantic proximity Read ↗

Association between methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms and essential hypertension: a systematic review and meta-analysis.Semantic proximity Read ↗

Association of methylenetetrahydrofolate reductase C677T and reduced-f carrier-1 G80A gene polymorphism with preeclampsia in Sudanese women.Semantic proximity Read ↗

The association of the placental MTHFR 3'-UTR polymorphisms, promoter methylation, and MTHFR expression with preeclampsia.Semantic proximity Read ↗

Polymorphisms of the methylenetetrahydrofolate reductase gene (C677T and A1298C) in nulliparous women complicated with preeclampsia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.