The Effect of Poly(ADP-ribose) Polymerase-1 Gene 3'Untranslated Region Polymorphism in Colorectal Cancer Risk among Saudi Cohort.

doi:10.1155/2016/8289293

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Article

The Effect of Poly(ADP-ribose) Polymerase-1 Gene 3'Untranslated Region Polymorphism in Colorectal Cancer Risk among Saudi Cohort.

Disease markers - 1 Jan 2016

Alhadheq Abdullah M, Purusottapatnam Shaik Jilani, Alamri Abdullah, Aljebreen Abdulrahman M, Alharbi Othman, Almadi Majid A, Alhadeq Faten, Azzam Nahla A, Semlali Abdelhabib, Alanazi Mohammad, Bazzi Mohammad D, Reddy Parine Narasimha

Abstract excerpt

Background. DNA repair systems are essential for each cell to repair and maintain the genome integrity. Base excision repair pathway is one of the crucial pathways to maintain genome integrity and PARP-1 plays a key role in BER pathway. The purpose of this study is to evaluate the association between polymorphisms in PARP-1 3'untranslated region (3'UTR) SNP rs8679 and its expression in colorectal cancer. Methods....

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PMID: 27746584
DOI: 10.1155/2016/8289293
PMCID: PMC5055945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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