Article
Novel mutations of the PARP-1 gene associated with colorectal cancer in the Saudi population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Alshammari Atika Hazzaa, Shalaby Manal Aly, Alanazi Mohammad Saud, Saeed Hesham Mahmoud
Abstract excerpt
BACKGROUND: Colorectal cancer (CRC) is the third most common type of cancers and the fourth leading cause of death worldwide. In Saudi Arabia, CRC accounts for 8.5% of all tumors; it ranks first among all cancers in males and third among females. The aim of this study was to link between different PARP-1 mutations and risk of CRC in Saudi population and to determine common variants of PARP-1 in Saudi CRC patients...
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