Article
Association of DNA repair gene polymorphisms with colorectal cancer risk and treatment outcomes.
Experimental and molecular pathology - 1 Apr 2020
Al-Shaheri Fawaz N, Al-Shami Kamal M, Gamal Eshrak H, Mahasneh Amjad A, Ayoub Nehad M
Abstract excerpt
Colorectal cancer (CRC) is the third most common carcinoma worldwide. Despite the progress in screening and treatment, CRC remains a leading cause of cancer-related mortality. Alterations to normal nucleic acid processing may drive neoplastic transformation of colorectal epithelium. DNA repair machinery performs an essential function in the protection of genome by reducing the number of genetic...
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