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DNA repair genes polymorphisms and risk of colorectal cancer in Saudi patients.

Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology - 1 Sept 2016

Karam Rehab A, Al Jiffry Bilal O, Al Saeed Mohamed, Abd El Rahman Tamer M, Hatem Mohamed, Amer Mona G

Abstract excerpt

BACKGROUND AND STUDY AIMS: Polymorphisms in the DNA repair genes may influence individual capacity to repair DNA damage, which may be associated with increased genetic instability and carcinogenesis. Our aim was to evaluate the relation of genetic polymorphisms in 2 DNA repair genes, XPD Lys751Gln and XRCC1 (A399G), with colorectal cancer (CRC) susceptibility. We further investigated the potential effect of these...

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Identifiers

PMID: 27686263
DOI: 10.1016/j.ajg.2016.08.005

Genes

XRCC1

Variants

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