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Article

Polymorphisms in genes of APE1, PARP1, and XRCC1: risk and prognosis of colorectal cancer in a northeast Chinese population.

Medical oncology (Northwood, London, England) - 1 Jun 2013

Li Ye, Li Shuying, Wu Zhiwei, Hu Fulan, Zhu Lin, Zhao Xiaojuan, Cui Binbin, Dong Xinshu, Tian Suli, Wang Fan, Zhao Yashuang

Abstract excerpt

Base excision repair (BER) pathway plays critical role in maintaining genome integrity. Polymorphisms in BER genes which modulate the DNA repair capacity may affect the susceptibility and prognosis of cancer. We conducted a case-control study and followed up the cases to explore the associations between BER genes polymorphisms and the risk and prognosis of colorectal cancer (CRC). This study included 451 CRC...

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Source

Identifiers

PMID: 23430444
DOI: 10.1007/s12032-013-0505-z

Genes

PARP1
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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