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Article

Engineering of temperature- and light-switchable Cas9 variants.

Nucleic acids research - 16 Nov 2016

Richter Florian, Fonfara Ines, Bouazza Boris, Schumacher Charlotte Helene, Bratovič Majda, Charpentier Emmanuelle, Möglich Andreas

Abstract excerpt

Sensory photoreceptors have enabled non-invasive and spatiotemporal control of numerous biological processes. Photoreceptor engineering has expanded the repertoire beyond natural receptors, but to date no generally applicable strategy exists towards constructing light-regulated protein actuators of arbitrary function. We hence explored whether the homodimeric Rhodobacter sphaeroides light-oxygen-voltage (LOV)...

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PMID: 27744350
DOI: 10.1093/nar/gkw930
PMCID: PMC5175372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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