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Article

The GABAergic septohippocampal connection is impaired in a mouse model of tauopathy.

Neurobiology of aging - 1 Jan 2017

Soler Helena, Dorca-Arévalo Jonatan, González Marta, Rubio Sara Esmeralda, Ávila Jesús, Soriano Eduardo, Pascual Marta

Abstract excerpt

Alzheimer's disease (AD), the most common cause of dementia nowadays, has been linked to alterations in the septohippocampal pathway (SHP), among other circuits in the brain. In fact, the GABAergic component of the SHP, which controls hippocampal rhythmic activity crucial for learning and memory, is altered in the J20 mouse model of AD-a model that mimics the amyloid pathology of this disease. However, AD is...

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Identifiers

PMID: 27743524
DOI: 10.1016/j.neurobiolaging.2016.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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