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Article

PIK3CA and AKT1 mutations in hidradenoma papilliferum.

Journal of clinical pathology - 1 May 2017

Goto Keisuke, Maeda Daichi, Kudo-Asabe Yukitsugu, Hibiya Takashi, Hayashi Akimasa, Fukayama Masashi, Ohashi Kenichi, Goto Akiteru

Abstract excerpt

AIMS: Hidradenoma papilliferum (HP) is a benign vulvar neoplasm that arises from anogenital mammary-like glands, and its morphology is similar to mammary intraductal papilloma. The aim of this study was to investigate oncogenic mutations involved in the tumourigenesis of HP. We focused specifically on PIK3CA and AKT1 mutations, which are both reported to be detected in 33% of mammary intraductal papillomas....

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Source

Identifiers

PMID: 27742746
DOI: 10.1136/jclinpath-2016-204003

Genes

AKT1
BRAF
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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