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Article

Frequent PIK3CA activating mutations in nipple adenomas.

Histopathology - 1 Jan 2017

Liau Jau-Yu, Lee Yi-Hsuan, Tsai Jia-Huei, Yuan Chang-Tsu, Chu Chia-Yu, Hong Jin-Bon, Sheen Yi-Shuan

Abstract excerpt

AIMS: Nipple adenoma (NA) is a rare benign epithelial tumour occurring in the nipple. Histologically, it exhibits variable and often mixed adenosis-like and usual ductal hyperplasia-like growth patterns. Morphologically, it is similar to other benign proliferative breast lesions occurring in the breast parenchyma, which have been shown to harbour activating mutations in PIK3CA, AKT1 or, less frequently, in RAS in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 27441415
DOI: 10.1111/his.13043

Genes

BRAF
AKT1
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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