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Article

Study of Selected BRCA1, BRCA2, and PIK3CA Mutations in Benign and Malignant Lesions of Anogenital Mammary-Like Glands.

The American Journal of dermatopathology - 1 May 2017

Konstantinova Anastasia M, Shelekhova Ksenya V, Imyanitov Evgeny N, Iyevleva Aglaya, Kacerovska Denisa, Michal Michal, Kazakov Dmitry V

Abstract excerpt

Anogenital mammary-like glands (AGMLGs) are nowadays considered a normal component of the anogenital area. Lesions involving AGMLGs are histopathologically very similar to their mammary counterparts, but the information on molecular biological mechanisms in these vulvar/perianal tumors is scarce. Mutations in the PI3K-AKT cascade have been found in hidradenoma papilliferum. The authors studied selected BRCA1,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28291131
DOI: 10.1097/DAD.0000000000000725

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Study of Selected BRCA1, BRCA2, and PIK3CA Mutations in Benign and Malignant Lesions of Anogenital Mammary-Like Glands.PMID 28291131Read ↗

Molecular alterations in lesions of anogenital mammary-like glands and their mammary counterparts including hidradenoma papilliferum, intraductal papilloma, fibroadenoma and phyllodes tumor.Semantic proximity Read ↗

Comprehensive profiling of the mutational landscape of hidradenoma papilliferum validates key role of alterations in the PI3K/AKT pathway alterationsSemantic proximity Read ↗

Frequent PIK3CA-activating mutations in hidradenoma papilliferums.Semantic proximity Read ↗

PIK3CA and AKT1 mutations in hidradenoma papilliferum.Semantic proximity Read ↗

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