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Article

The genetic architecture of breast papillary lesions as a predictor of progression to carcinoma

12 Mar 2020

Abstract excerpt

Abstract Intraductal papillomas (IDP) are challenging breast findings because of their variable risk of progression to malignancy. The molecular events driving IDP development and genomic features of malignant progression are poorly understood. In this study, genome-wide CNA and/or targeted mutation analysis was performed on 44 cases of IDP, of which 20 cases had coexisting ductal carcinoma in situ (DCIS),...

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PMID: 32195332
DOI: 10.1038/s41523-020-0150-6

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