Interleukin-18 gene polymorphism and risk of CVD in older patients with type 2 diabetes mellitus.

doi:10.1016/j.diabres.2016.09.021

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Interleukin-18 gene polymorphism and risk of CVD in older patients with type 2 diabetes mellitus.

Diabetes research and clinical practice - 1 Nov 2016

Buraczynska Monika, Ksiazek Katarzyna, Zukowski Pawel, Grzebalska Agnieszka

Abstract excerpt

OBJECTIVE: Interleukin-18 (IL-18), a proinflammatory cytokine, plays a key role in the acute and chronic inflammatory processes. It is associated with risk of developing cardiovascular disease (CVD). The aim of this study was to evaluate association between G(-137)C polymorphism (rs187238) in the IL-18 gene and risk of diabetes and CVD in type 2 diabetes patients. METHODS: We examined 1548 T2DM patients and 590...

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PMID: 27741477
DOI: 10.1016/j.diabres.2016.09.021

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