Article
No association between interleukin-18 levels and risk of cardiovascular disease: A Mendelian randomization study.
Hereditas - 7 Apr 2020
Fan Siyu, He Pan, Guan Jieqiong, Song Wenjing, Zhi Hong, Wang Lina
Abstract excerpt
OBJECTIVE: In this study, Mendelian randomization method was used to determine whether there was a causal association between inflammatory cytokine IL-18 and cardiovascular disease risk. METHODS: We performed a meta-analysis to evaluate the association between IL-18-137G/C and -607C/A polymorphisms and phenotype of IL-18 levels, and also the risks of CVD. All the literatures were searched before September 30,...
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