Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of IL-18 promoter polymorphisms with predisposition to Type 1 diabetes.

Diabetic medicine : a journal of the British Diabetic Association - 1 Mar 2006

Mojtahedi Z, Naeimi S, Farjadian S, Omrani G R, Ghaderi A

Abstract excerpt

AIMS: IL-18, a potent IFN-gamma-inducing cytokine, is capable of polarizing the immune response to a Th1 phenotype. Recent studies have demonstrated an association between single-nucleotide polymorphisms located at positions -607 (A/C) and -137 (C/G) in the promoter region of IL-18 gene and Type 1 diabetes. The aim of the present study was to determine whether the same polymorphisms of the gene were associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Haplotypes

Share to Interleukin-18

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 16492204
DOI: 10.1111/j.1464-5491.2006.01786.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of IL-18 promoter polymorphisms with predisposition to Type 1 diabetes.PMID 16492204Read ↗

Interleukin-18 promoter polymorphisms in type 1 diabetes.Semantic proximity Read ↗

Association of polymorphisms in the IL-18 and IL-12 genes with susceptibility to Type 1 diabetes in Turkish patients.Semantic proximity Read ↗

Interleukin-18 promoter -607 C/A and -137 G/C polymorphisms and susceptibility to type 1 diabetes: A meta-analysis.Semantic proximity Read ↗

Interleukin 18 (IL18) gene promoter polymorphisms are associated with type 1 diabetes mellitus in Brazilian patients.Semantic proximity Read ↗

Interleukin IL-18 gene promoter polymorphisms in adult patients with type 1 diabetes mellitus and latent autoimmune diabetes in adults.Semantic proximity Read ↗

Association of interleukin-18 gene promoter polymorphisms in type 1 diabetes and autoimmune thyroid disease.Semantic proximity Read ↗

Interleukin-18 gene polymorphism and risk of CVD in older patients with type 2 diabetes mellitus.Semantic proximity Read ↗

Interleukin-18 promoter -137 G/C polymorphism (rs187238) is associated with biochemical markers of renal function and cardiovascular disease in type 2 diabetes patients.Semantic proximity Read ↗

Interleukin-18 promoter gene polymorphisms in Chinese patients with systemic lupus erythematosus: association with CC genotype at position -607.Semantic proximity Read ↗

A meta-analysis evaluating the relationship between IL-18 gene promoter polymorphisms and an individual's susceptibility to HCV infection.Semantic proximity Read ↗

Interleukin-18 -137 G/C and -607 C/A polymorphisms and Alzheimer's disease risk: a meta-analysis.Semantic proximity Read ↗

Association between IL-18 gene promoter polymorphisms and inflammatory bowel disease in a Japanese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.