Article
Interleukin-18 promoter -607 C/A and -137 G/C polymorphisms and susceptibility to type 1 diabetes: A meta-analysis.
Human immunology - 1 Aug 2015
Lee Young Ho, Kim Jae-Hoon, Song Gwan Gyu
Abstract excerpt
OBJECTIVE: The aim of this study was to determine whether the functional interleukin-18 (IL-18) promoter -607 C/A (rs1946518) and -137 G/C (rs187238) polymorphisms are associated with susceptibility to type 1 diabetes (TID). METHODS: A meta-analysis was conducted to assess the associations between the IL-18 -607 C/A and -137 G/C polymorphisms and T1D in overall and by ethnic group. RESULTS: A total of 6075 cases...
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