Article
Evaluation of Hs-CRP levels and interleukin 18 (-137G/C) promoter polymorphism in risk prediction of coronary artery disease in first degree relatives.
PloS one - 1 Jan 2015
G Rajesh Kumar, K Mrudula Spurthi, G Kishore Kumar, Kurapati Mohanalatha, M Saraswati, T Mohini Aiyengar, P Chiranjeevi, G Srilatha Reddy, S Nivas, P Kaushik, K Sanjib Sahu, H Surekha Rani
Abstract excerpt
BACKGROUND: Coronary Artery Disease (CAD) is clearly a multifactorial disease that develops from childhood and ultimately leads to death. Several reports revealed having a First Degree Relatives (FDRS) with premature CAD is a significant autonomous risk factor for CAD development. C - reactive protein (CRP) is a member of the pentraxin family and is the most widely studied proinflammatory biomarker. IL-18 is a...
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