Article
Association of interleukin-18 promoter polymorphism and atherosclerotic diseases in Chinese patients with diabetic nephropathy.
Nephrology (Carlton, Vic.) - 1 Sept 2009
Szeto Cheuk-Chun, Chow Kai-Ming, Poon Peter Yam-Kau, Kwan Bonnie Ching-Ha, Li Philip Kam-Tao
Abstract excerpt
AIM: Interleukin-18 (IL-18) is a pro-inflammatory cytokine and possibly plays an important role in the pathogenesis of cardiovascular disease. The relationship between two IL-18 gene polymorphisms, namely C-607A and G-137C, and cardiovascular disease in patients with diabetic nephropathy was examined. METHODS: Two hundred and twenty patients (91 male) with diabetic nephropathy were studied. The IL-18 promoter...
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