Article
An extraction-free method for rapid detection of CYP2C19 * 2/3/17 polymorphisms in one tube using melting curve analysis.
Biotechnology journal - 1 Nov 2023
Guo Jianguang, You Weixin, Lin Kangfeng, Li Qinghan, Guo Xiangju, Wang Shuai, Bian Ya, Ren Wenjing, Zhang Rui, Wang Yanping, Li Boan
Abstract excerpt
Drug-metabolizing enzymes play an important role in the metabolism of drugs in vivo. Their activity is an important factor affecting the rate of drug metabolism, which directly determines the intensity and persistence of drug action. Patients taking medication can be divided into different metabolic types through detection of CYP2C19 drug-metabolizing enzyme gene polymorphisms, which can then be used for...
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