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Article

Three Gene Signature for Predicting the Development of Hepatocellular Carcinoma in Chronically Infected Hepatitis C Virus Patients.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Dec 2016

Ibrahim Marwa K, Salama Hosny, Abd El Rahman Mohamad, Dawood Reham M, Bader El Din Noha G, Salem Heba F, Abdelrahim Mohamed E A, Omran Dalia, Omran Moataza H, El-Wakeel Khaled Helmi, Abdelhafez Tawfeek H, Khedr Ahmed, El Awady Mostafa K

Abstract excerpt

Hepatitis C virus (HCV) is the leading cause of liver fibrosis and hepatocellular carcinoma (HCC). At present, there is no predictive biomarker for the patients at high risk of developing HCC. In this study, we examined the association between single-nucleotide polymorphisms (SNPs) in 3 innate immunity genes [2'-5'oligoadenylate synthetase 1 (OAS1) rs10774671, interleukin 28B (IL28B) rs12979860, and low molecular...

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Share to 2',5'-Oligoadenylate Synthetase
Share to Carcinoma, Hepatocellular
Share to Cytoskeletal Proteins
Share to Hepatitis C, Chronic
Share to Interferons
Share to Interleukins
Share to LIM Domain Proteins
Share to Liver Cirrhosis

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Identifiers

PMID: 27726464
DOI: 10.1089/jir.2016.0042

Genes

OAS1

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