Interleukin 28 Polymorphisms and Hepatocellular Carcinoma Development after Direct Acting Antiviral Therapy for Chronic Hepatitis C.

doi:10.15403/jgld-309

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Interleukin 28 Polymorphisms and Hepatocellular Carcinoma Development after Direct Acting Antiviral Therapy for Chronic Hepatitis C.

Journal of gastrointestinal and liver diseases : JGLD - 9 Dec 2019

Simili Angelo, Mazzella Giuseppe, Ravaioli Federico, Festi Davide, Bacchi-Reggiani Maria Letizia, Porro Alberto, Bazzoli Franco, Azzaroli Francesco

Abstract excerpt

BACKGROUND AND AIMS: Cirrhotic patients with hepatitis C virus (HCV) infection remain at risk of developing hepatocellular carcinoma (HCC) even after the sustained virologic response (SVR). We aimed to evaluate whether the IL28 (rs12979860) single nucleotide polymorphism (SNP) may constitute a predisposing genetic factor and to identify the SVR patients at risk of HCC. METHODS: Two hundred patients undergoing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Hepatocellular

Share to Hepatitis C, Chronic

Share to Interferons

Share to Liver Neoplasms

Share to Neoplasm Recurrence, Local

Share to Sustained Virologic Response

Share to Vitamin A

Source

Open in PubMed

Identifiers

PMID: 31826071
DOI: 10.15403/jgld-309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interleukin 28 Polymorphisms and Hepatocellular Carcinoma Development after Direct Acting Antiviral Therapy for Chronic Hepatitis C.PMID 31826071Read ↗

Influence of interleukin-28B polymorphism on progression to hepatitis virus-induced hepatocellular carcinoma.Semantic proximity Read ↗

IL-28B rs12979860 polymorphism affect the course of chronic hepatitis and the development of HCC in Egyptian patients with hepatitis C type 4.Semantic proximity Read ↗

The influence of interleukin 28B polymorphisms on the risk of hepatocellular carcinoma among patients with HBV or HCV infectionSemantic proximity Read ↗

Genetic variation near interleukin 28B and the risk of hepatocellular carcinoma in patients with chronic hepatitis C.Semantic proximity Read ↗

Role of IL28B polymorphism in the development of hepatitis C virus-induced hepatocellular carcinoma, graft fibrosis, and posttransplant antiviral therapy.Semantic proximity Read ↗

Association of the interleukin-28B gene polymorphism with development of hepatitis virus-related hepatocellular carcinoma and liver cirrhosis: a meta-analysis.Semantic proximity Read ↗

Risk of Hepatocellular Carcinoma after HCV Clearance by Direct-Acting Antivirals Treatment Predictive Factors and Role of EpigeneticsSemantic proximity Read ↗

IL-28B rs12979860 C/T allele distribution in patients with liver cirrhosis: role in the course of chronic viral hepatitis and the development of HCC.Semantic proximity Read ↗

IL28B polymorphism may guide pegylated interferon plus ribavirin therapy even after curative treatment for hepatitis C virus-related hepatocellular carcinoma.Semantic proximity Read ↗

Genetic variation in IL28B is associated with the development of hepatitis B-related hepatocellular carcinoma.Semantic proximity Read ↗

Interleukin-28B TT genotype is frequently found in patients with hepatitis C virus cirrhosis but does not influence hepatocarcinogenesis.Semantic proximity Read ↗

Impact of IL28B genetic variation on HCV-induced liver fibrosis, inflammation, and steatosis: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.