Article
IL-28B rs12979860 polymorphism affect the course of chronic hepatitis and the development of HCC in Egyptian patients with hepatitis C type 4.
British journal of biomedical science - 1 Oct 2018
Attallah A M, Omran D, Marie M S, Abdelrazek Mohamed, Salama A, El Essawey R, Mobarak L, Maklad S, Omar A
Abstract excerpt
BACKGROUND: A single nucleotide polymorphism (SNP) in the interleukin 28B (IL28B) gene may alter the trajectory of hepatitis C virus (HCV) chronic infection. Several studies have sought to determine a link between IL28B rs12979860 SNP and the development of HCV-related hepatocellular carcinoma (HCC), but with variable results, and consensus is awaited. We hypothesised that IL28B rs12979860 SNP is linked to HCC in...
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