Impact of OAS1 Exon 7 rs10774671 Genetic Variation on Liver Fibrosis Progression in Egyptian HCV Genotype 4 Patients.

doi:10.1089/vim.2015.0041

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Impact of OAS1 Exon 7 rs10774671 Genetic Variation on Liver Fibrosis Progression in Egyptian HCV Genotype 4 Patients.

Viral immunology - 1 Nov 2015

Bader El Din Noha G, Anany Mohamed A, Dawood Reham M, Ibrahim Marwa K, El-Shenawy Reem, El Abd Yasmin S, El Awady Mostafa K

Abstract excerpt

The aim of this study was to assess the impact of genetic variants of oligoadenylate synthetase 1 (OAS1) single-nucleotide polymorphism (SNP) rs10774671 at the exon 7 splice acceptor site on liver fibrosis progression and hepatitis C virus (HCV) outcome in Egyptian HCV genotype 4 patients. In this study, 195 subjects were enrolled; 60 controls and 135 chronic HCV genotype 4 patients with different fibrosis...

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PMID: 26505957
DOI: 10.1089/vim.2015.0041

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OAS1

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