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Article

Hemizygous Deletion on Chromosome 3p26.1 Is Associated with Heavy Smoking among African American Subjects in the COPDGene Study.

PloS one - 1 Jan 2016

Begum Ferdouse, Ruczinski Ingo, Hokanson John E, Lutz Sharon M, Parker Margaret M, Cho Michael H, Hetmanski Jacqueline B, Scharpf Robert B, Crapo James D, Silverman Edwin K, Beaty Terri H

Abstract excerpt

Many well-powered genome-wide association studies have identified genetic determinants of self-reported smoking behaviors and measures of nicotine dependence, but most have not considered the role of structural variants, such as copy number variation (CNVs), influencing these phenotypes. Here, we included 2,889 African American and 6,187 non-Hispanic White subjects from the COPDGene cohort...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27711239
DOI: 10.1371/journal.pone.0164134
PMCID: PMC5053531

Genes

GRM7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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