Article
Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.
The Lancet. Respiratory medicine - 1 Mar 2014
Cho Michael H, McDonald Merry-Lynn N, Zhou Xiaobo, Mattheisen Manuel, Castaldi Peter J, Hersh Craig P, Demeo Dawn L, Sylvia Jody S, Ziniti John, Laird Nan M, Lange Christoph, Litonjua Augusto A, Sparrow David, Casaburi Richard, Barr R Graham, Regan Elizabeth A, Make Barry J, Hokanson John E, Lutz Sharon, Dudenkov Tanda Murray, Farzadegan Homayoon, Hetmanski Jacqueline B, Tal-Singer Ruth, Lomas David A, Bakke Per, Gulsvik Amund, Crapo James D, Silverman Edwin K, Beaty Terri H
Abstract excerpt
BACKGROUND: The genetic risk factors for susceptibility to chronic obstructive pulmonary disease (COPD) are still largely unknown. Additional genetic variants are likely to be identified by genome-wide association studies in larger cohorts or specific subgroups. We sought to identify risk loci for moderate to severe and severe COPD with data from several cohort studies. METHODS: We combined genome-wide...
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