Article
Genetic epidemiology of COPD (COPDGene) study design.
COPD - 1 Feb 2010
Regan Elizabeth A, Hokanson John E, Murphy James R, Make Barry, Lynch David A, Beaty Terri H, Curran-Everett Douglas, Silverman Edwin K, Crapo James D
Abstract excerpt
BACKGROUND: COPDGene is a multicenter observational study designed to identify genetic factors associated with COPD. It will also characterize chest CT phenotypes in COPD subjects, including assessment of emphysema, gas trapping, and airway wall thickening. Finally, subtypes of COPD based on these phenotypes will be used in a comprehensive genome-wide study to identify COPD susceptibility genes. METHODS/RESULTS:...
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