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Article

The impact of genetic variation and cigarette smoke on DNA methylation in current and former smokers from the COPDGene study.

Epigenetics - 1 Jan 2015

Qiu Weiliang, Wan Emily, Morrow Jarrett, Cho Michael H, Crapo James D, Silverman Edwin K, DeMeo Dawn L

Abstract excerpt

DNA methylation can be affected by systemic exposures, such as cigarette smoking and genetic sequence variation; however, the relative impact of each on the epigenome is unknown. We aimed to assess if cigarette smoking and genetic variation are associated with overlapping or distinct sets of DNA methylation marks and pathways. We selected 85 Caucasian current and former smokers with genome-wide single nucleotide...

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Identifiers

PMID: 26646902
DOI: 10.1080/15592294.2015.1106672
PMCID: PMC4844199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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