Article
The Pol30-K196 residue plays a critical role in budding yeast DNA postreplication repair through interaction with Rad18.
DNA repair - 1 Nov 2016
Fan Li, Xiao Wei
Abstract excerpt
PCNA plays critical roles in DNA replication and various DNA repair pathways including DNA damage tolerance (DDT). In budding yeast Saccharomyces cerevisiae, DDT (aka DNA postreplication repair, PRR) is achieved by sequential ubiquitination of PCNA encoded by POL30. Our previous studies revealed that two Arabidopsis PCNA genes were able to complement the essential function of POL30 in budding yeast, but failed to...
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