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Article

Spartan/C1orf124 is important to prevent UV-induced mutagenesis.

Cell cycle (Georgetown, Tex.) - 15 Sept 2012

Machida Yuka, Kim Myoung Shin, Machida Yuichi J

Abstract excerpt

Uninterrupted replication across damaged DNA is critical to prevent replication fork collapse and resulting double-strand DNA breaks. Rad18-mediated PCNA ubiquitination is a crucial event that triggers a number of downstream pathways important for lesion bypass. Here, we report characterization of Spartan, an evolutionarily conserved protein containing a PCNA-interacting peptide motif, called a PIP box, and a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22894931
DOI: 10.4161/cc.21694
PMCID: PMC3466550

Genes

PCNA
PIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Spartan/C1orf124 is important to prevent UV-induced mutagenesis.PMID 22894931Read ↗

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