Article
Prognostic significance of novel katG mutations in Mycobacterium tuberculosis.
International journal of mycobacteriology - 1 Mar 2015
Valafar F, Ramirez-Busby S M, Torres J, Paul Lynthia V, Rodwell T C, Victor T C, Rodrigues C, Gler M T, Crudu V, Catanzaro T
Abstract excerpt
BACKGROUND: By using whole genome sequencing (WGS), researchers are beginning to understand the genetic diversity of Mycobacterium tuberculosis (MTB) and its consequences for the diagnosis of multidrug-resistant tuberculosis (MDR-TB) on a genomic scale. The Global Consortium for Drug-resistant TB Diagnostics (GCDD) conducted a genome scale variant analyses of 366 clinical MTB genomes (mostly MDR/XDR [extensively...
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