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Diversity and novel mutations in membrane transporters of Mycobacterium tuberculosis.

Briefings in functional genomics - 13 Apr 2023

Khan Muhammad Tahir, Khan Taj Ali, Ahmad Irshad, Muhammad Shabbir, Wei Dong-Qing

Abstract excerpt

Mycobacterium tuberculosis (MTB), the causative agent of tuberculosis (TB), encodes a family of membrane proteins belonging to Resistance-Nodulation-Cell Division (RND) permeases also called multidrug resistance pumps. Mycobacterial membrane protein Large (MmpL) transporters represent a subclass of RND transporters known to participate in exporting of lipid components across the cell envelope. These proteins...

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PMID: 35868449
DOI: 10.1093/bfgp/elac018

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