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Article

Can mycobacterial katG genetic changes in isoniazid-resistant tuberculosis influence human disease features?

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 May 2013

Escalante P, McKean-Cowdin R, Ramaswamy S V, Williams-Bouyer N, Teeter L D, Jones B E, Graviss E A

Abstract excerpt

BACKGROUND: Isoniazid-resistant (INHr) Mycobacterium tuberculosis isolates often have katG mutations, and katG is a virulence factor in animal models. It is unclear if katG mutations or other mutations influence the characteristics of human disease. OBJECTIVE: To determine if the presence of INHr-conferring mutations were associated with distinct clinical features of tuberculosis (TB). METHODS: In a retrospective...

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Identifiers

PMID: 23453008
DOI: 10.5588/ijtld.12.0380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Can mycobacterial katG genetic changes in isoniazid-resistant tuberculosis influence human disease features?PMID 23453008Read ↗

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