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Predicting Drug Resistance in Mycobacterium tuberculosis: A Machine Learning Approach to Genomic Mutation Analysis

24 Jan 2025

Abstract excerpt

Background/Objectives: Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tuberculosis), remains a leading cause of death from infectious diseases globally. The treatment of active TB relies on first- and second-line drugs, however, the emergence of drug resistance poses a significant challenge to global TB control efforts. Recent advances in whole-genome sequencing combined with machine learning have...

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PMID: 39941209
DOI: 10.3390/diagnostics15030279

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