Article
Identification and analysis of mutations in the katG gene in multidrug-resistant Mycobacterium tuberculosis clinical isolates.
Pneumonologia i alergologia polska - 1 Jan 2013
Jagielski Tomasz, Grzeszczuk Magdalena, Kamiński Michał, Roeske Katarzyna, Napiórkowska Agnieszka, Stachowiak Radosław, Augustynowicz-Kopeć Ewa, Zwolska Zofia, Bielecki Jacek
Abstract excerpt
INTRODUCTION: A major role in the development of resistance of Mycobacterium tuberculosis to isoniazid (INH) is attributed to mutations in the katG gene coding for the catalase/peroxidase, an enzyme required for obtaining a pharmacologically active form of the drug. Analysis of mutations in the k...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
