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Article

Deficits in inhibition and flexibility are associated with the APOE-E4 allele in nondemented older adults.

Journal of clinical and experimental neuropsychology - 1 Nov 2005

Wetter Spencer R, Delis Dean C, Houston Wes S, Jacobson Mark W, Lansing Amy, Cobell Krystal, Salmon David P, Bondi Mark W

Abstract excerpt

This prospective study of nondemented older adults at genetic risk for AD and other types of dementia (i.e., APOE e4 allele) utilized a new Stroop test that includes a dual executive-function condition requiring both response inhibition and cognitive switching. Results indicated that, relative to non-e4 subjects, the e4 group committed more errors, but only on the new Inhibition/Switching condition. In addition,...

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Source

Identifiers

PMID: 16207619
DOI: 10.1080/13803390490919001

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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