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Article

ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor

3 Feb 2011

Abstract excerpt

The adenosine deaminases acting on RNA (ADAR) enzymes catalyse conversion of adenosine to inosine in dsRNA. A positive effect of ADAR1 on human immunodeficiency virus type 1 (HIV-1) replication has recently been reported. Here, we show that another ADAR enzyme, ADAR2, positively affects the replication process of HIV-1. We found that, analogously to ADAR1, ADAR2 enhances the release of progeny virions by an...

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PMID: 21289159
DOI: 10.1099/vir.0.028043-0

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