Article
A highly specific sodium aptamer probed by 2-aminopurine for robust Na+ sensing.
Nucleic acids research - 1 Dec 2016
Zhou Wenhu, Ding Jinsong, Liu Juewen
Abstract excerpt
Sodium is one of the most abundant metals in the environment and in biology, playing critical ecological and physiological roles. Na+ is also the most common buffer salt for nucleic acids research, while its specific interaction with DNA has yet to be fully studied. Herein, we probe a highly selective and robust Na+ aptamer using 2-aminopurine (2AP), a fluorescent adenine analog. This aptamer has two DNA strands...
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