Article
Clinical and brain imaging characteristics in leucine-rich repeat kinase 2-associated PD and asymptomatic mutation carriers.
Movement disorders : official journal of the Movement Disorder Society - 1 Nov 2011
Brockmann Kathrin, Gröger Adriane, Di Santo Adriana, Liepelt Inga, Schulte Claudia, Klose Uwe, Maetzler Walter, Hauser Ann-Kathrin, Hilker Ruediger, Gomez-Mancilla Baltazar, Berg Daniela, Gasser Thomas
Abstract excerpt
The objective of this research was to evaluate a possible endophenotype in leucine-rich repeat kinase 2 (LRRK2)-associated Parkinson's disease (PD). Ten symptomatic LRRK2 patients, 24 sporadic Parkinson's disease patients as well as 10 asymptomatic LRRK2 mutation carriers and 29 matched healthy controls underwent comprehensive clinical assessments with respect to motor and non-motor symptoms. Transcranial...
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