Article
Neural correlates of executive functions in healthy G2019S LRRK2 mutation carriers.
Cortex; a journal devoted to the study of the nervous system and behavior - 1 Oct 2013
Thaler Avner, Mirelman Anat, Helmich Rick C, van Nuenen Bart F L, Rosenberg-Katz Keren, Gurevich Tanya, Orr-Urtreger Avi, Marder Karen, Bressman Susan, Bloem Bastiaan R, Giladi Nir, Hendler Talma
Abstract excerpt
INTRODUCTION: The G2019S mutation in the leucine rich repeat kinase 2 (LRRK2) gene is prevalent among Ashkenazi Jewish patients with Parkinson's disease (PD). Cognitive deficits are common in early stage PD. We aimed to characterize the effect of the G2019S mutation on neural mechanisms of executive function processing by testing whether healthy mutation carriers who are an "at risk" population for the future...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.