Article
Mutational spectrum of tobacco associated oral squamous carcinoma and its therapeutic significance.
World journal of surgical oncology - 27 Nov 2019
Batta Nishant, Pandey Manoj
Abstract excerpt
Oral squamous cell cancer (OSCC) is a common malignancy attributed to use of chewing smokeless tobacco and smoking. Most of the targeted strategies are based on EGFR expression and mutation; however, none of them has shown significant improvement in survival and response rates. We carried out this study to evaluate mutational profile of tobacco associated oral carcinoma with special emphasis on EGFR and its...
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