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Article

Dynamics and Correlates of CD8 T-Cell Counts in Africans with Primary Human Immunodeficiency Virus Type 1 Infection.

Journal of virology - 15 Nov 2016

Prentice Heather A, Lu Hailin, Price Matthew A, Kamali Anatoli, Karita Etienne, Lakhi Shabir, Sanders Eduard J, Anzala Omu, Allen Susan, Goepfert Paul A, Hunter Eric, Gilmour Jill, Tang Jianming

Abstract excerpt

In individuals with HIV-1 infection, depletion of CD4+ T cells is often accompanied by a malfunction of CD8+ T cells that are persistently activated and/or exhausted. While the dynamics and correlates of CD4 counts have been well documented, the same does not apply to CD8 counts. Here, we examined the CD8 counts in a cohort of 497 Africans with primary HIV-1 infection evaluated in monthly to quarterly follow-up...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27630231
DOI: 10.1128/JVI.01467-16
PMCID: PMC5105675

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