The influence of human leukocyte antigen class I alleles and their population frequencies on human immunodeficiency virus type 1 control among African Americans.

doi:10.1016/j.humimm.2011.01.003

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Article

The influence of human leukocyte antigen class I alleles and their population frequencies on human immunodeficiency virus type 1 control among African Americans.

Human immunology - 1 Apr 2011

Lazaryan Aleksandr, Song Wei, Lobashevsky Elena, Tang Jianming, Shrestha Sadeep, Zhang Kui, McNicholl Janet M, Gardner Lytt I, Wilson Craig M, Klein Robert S, Rompalo Anne, Mayer Kenneth, Sobel Jack, Kaslow Richard A

Abstract excerpt

Populations of African ancestry continue to account for a disproportionate burden of the human immunodeficiency virus type 1 (HIV-1) epidemic in the United States. We investigated the effects of human leukocyte antigen (HLA) class I markers in association with virologic and immunologic control of HIV-1 infection among 338 HIV-1 subtype B-infected African Americans in 2 cohorts: Reaching for Excellence in...

Topics

Adolescent
Adult
Black or African American
Alleles
CD4 Lymphocyte Count
Female
Gene Frequency
Genetic Association Studies
HIV Infections
HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Histocompatibility Antigens Class I

Humans

Linkage Disequilibrium

Male

Middle Aged

Viral Load

Young Adult

Source

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Identifiers

PMID: 21262311
DOI: 10.1016/j.humimm.2011.01.003
PMCID: PMC3778654

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