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Article

Different modes of variation for each BG lineage suggest different functions.

Open biology - 1 Sept 2016

Chattaway John, Ramirez-Valdez R Andrei, Chappell Paul E, Caesar Joseph J E, Lea Susan M, Kaufman Jim

Abstract excerpt

Mammalian butyrophilins have various important functions, one for lipid binding but others as ligands for co-inhibition of αβ T cells or for stimulation of γδ T cells in the immune system. The chicken BG homologues are dimers, with extracellular immunoglobulin variable (V) domains joined by cysteines in the loop equivalent to complementarity-determining region 1 (CDR1). BG genes are found in three genomic...

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Identifiers

PMID: 27628321
DOI: 10.1098/rsob.160188
PMCID: PMC5043582

Genes

CDR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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