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Article

Evolutionary history of black grouse major histocompatibility complex class IIB genes revealed through single locus sequence-based genotyping.

BMC genetics - 24 Apr 2013

Strand Tanja, Wang Biao, Meyer-Lucht Yvonne, Höglund Jacob

Abstract excerpt

BACKGROUND: Gene duplications are frequently observed in the Major Histocompatibility Complex (MHC) of many species, and as a consequence loci belonging to the same MHC class are often too similar to tell apart. In birds, single locus genotyping of MHC genes has proven difficult due to concerted evolution homogenizing sequences at different loci. But studies on evolutionary history, mode of selection and...

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PMID: 23617616
DOI: 10.1186/1471-2156-14-29
PMCID: PMC3652749

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