Article
Organisation and diversity of the class II DM region of the chicken MHC.
Molecular immunology - 1 May 2011
Chazara Olympe, Tixier-Boichard Michèle, Morin Véronique, Zoorob Rima, Bed'hom Bertrand
Abstract excerpt
In mammals, the DM molecules are encoded by the major histocompatibility complex (MHC) and execute key functions in the class II antigen presentation pathway. Here, we characterised three DM genes in the MHC B region of the chicken (Gallus gallus): B-DMA, B-DMB1 and B-DMB2. They encode one class II DM α chain and two β chains, exhibiting motifs of chicken class II molecules as well as specificities of mammal DM...
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