Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Different evolutionary histories of the two classical class I genes BF1 and BF2 illustrate drift and selection within the stable MHC haplotypes of chickens.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 2007

Shaw Iain, Powell Timothy J, Marston Denise A, Baker Ken, van Hateren Andrew, Riegert Patricia, Wiles Michael V, Milne Sarah, Beck Stephan, Kaufman Jim

Abstract excerpt

Compared with the MHC of typical mammals, the chicken MHC (BF/BL region) of the B12 haplotype is smaller, simpler, and rearranged, with two classical class I genes of which only one is highly expressed. In this study, we describe the development of long-distance PCR to amplify some or all of each class I gene separately, allowing us to make the following points. First, six other haplotypes have the same genomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chickens
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression

Share to Genes, MHC Class I

Share to Genetic Drift

Share to Haplotypes

Share to Histocompatibility Antigens Class I

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 17442958
DOI: 10.4049/jimmunol.178.9.5744

Genes

TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Different evolutionary histories of the two classical class I genes BF1 and BF2 illustrate drift and selection within the stable MHC haplotypes of chickens.PMID 17442958Read ↗

The chicken BF1 (classical MHC class I) gene shows evidence of selection for diversity in expression and in promoter and signal peptide regions.Semantic proximity Read ↗

Contribution of mutation, recombination, and gene conversion to chicken MHC-B haplotype diversity.Semantic proximity Read ↗

Minor differences in peptide presentation between chicken MHC class I molecules can explain differences in disease susceptibilitySemantic proximity Read ↗

Simplifying principles underlying the highly complex peptide motif of the promiscuous chicken MHC class I molecule, BF2*21:01Semantic proximity Read ↗

Genetic characterization of the TAPBP and its allelic association with BF2 in the chicken major histocompatibility complex.Semantic proximity Read ↗

The properties of the single chicken MHC classical class II alpha chain ( B-LA) gene indicate an ancient origin for the DR/E-like isotype of class II molecules.Semantic proximity Read ↗

Genetic Characterization of the <i>TAPBP</i> and Its Haplotypic Association with <i>BF2</i> in the Chicken Major Histocompatibility ComplexSemantic proximity Read ↗

Two class I genes of the chicken MHC have different functions: BF1 is recognized by NK cells while BF2 is recognized by CTLsSemantic proximity Read ↗

Genetic insights into the major histocompatibility complex class I BF2 gene of Korean native chickens in relation to the LEI0258 microsatellite marker and the 90-SNP panel.Semantic proximity Read ↗

Single locus typing of MHC class I and class II B loci in a population of red jungle fowl.Semantic proximity Read ↗

MHC class I BFIV gene polymorphisms in four Chinese native chicken breeds.Semantic proximity Read ↗

Narrow groove and restricted anchors of MHC class I molecule BF2*0401 plus peptide transporter restriction can explain disease susceptibility of B4 chickens.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.