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Article

Transcriptional Timers Regulating Mitosis in Early Drosophila Embryos.

Cell reports - 13 Sept 2016

Momen-Roknabadi Amir, Di Talia Stefano, Wieschaus Eric

Abstract excerpt

The development of an embryo requires precise spatiotemporal regulation of cellular processes. During Drosophila gastrulation, a precise temporal pattern of cell division is encoded through transcriptional regulation of cdc25(string) in 25 distinct mitotic domains. Using a genetic screen, we demonstrate that the same transcription factors that regulate the spatial pattern of cdc25(string) transcription encode its...

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Identifiers

PMID: 27626650
DOI: 10.1016/j.celrep.2016.08.034
PMCID: PMC5386176

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