Article
Pairing of segmentation clock genes drives robust pattern formation.
Nature - 1 Jan 2021
Zinani Oriana Q H, Keseroğlu Kemal, Ay Ahmet, Özbudak Ertuğrul M
Abstract excerpt
Gene expression is an inherently stochastic process1,2; however, organismal development and homeostasis require cells to coordinate the spatiotemporal expression of large sets of genes. In metazoans, pairs of co-expressed genes often reside in the same chromosomal neighbourhood, with gene pairs representing 10 to 50% of all genes, depending on the species3-6. Because shared upstream regulators can ensure...
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