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Article

Number of nuclear divisions in the Drosophila blastoderm controlled by onset of zygotic transcription.

Current biology : CB - 21 Jan 2013

Sung Hung-wei, Spangenberg Saskia, Vogt Nina, Großhans Jörg

Abstract excerpt

The cell number of the early Drosophila embryo is determined by exactly 13 rounds of synchronous nuclear divisions, allowing cellularization and formation of the embryonic epithelium. The pause in G2 in cycle 14 is controlled by multiple pathways, such as activation of DNA repair checkpoint, progression through S phase, and inhibitory phosphorylation of Cdk1, involving the genes grapes, mei41, and wee1. In...

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PMID: 23290555
DOI: 10.1016/j.cub.2012.12.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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